Nitric Oxide Stimulator


Nitric Oxide (NO) is a very important signaling molecule that acts in many tissues to regulate a wide range of physiological processes.

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Healthy Heart & Immune System Blend
It was first discovered several years ago by a group that was attempting to identify the agent responsible for promoting blood vessel relaxation and the regulation of vascular tone. This particular agent was named endothelium-derived relaxing factor (EDRF), and was initially assumed to be a protein like most of the other signaling factors previously discovered. (NO) plays a key role in many biological processes including immune defense, neurotransmission, and the regulation of cell death (apoptosis). Since NO is such a very small molecule, it is able to diffuse rapidly across cell membrane and depending on the conditions, is able to travel several hundred microns. Nitric oxide is produced by enzymes known as nitric oxide syntheses (NOS).

Nitric Oxide Syntheses:
Nitric Oxide (NO) is produced by a group of enzymes called nitric oxide syntheses (NOS). These enzymes (present in body) convert the Arginine in our Arginine alpha-Ketoglutarate (AKG) into Citrulline, producing NO in the process. Oxygen and NADPH are necessary co-factors. More blood flow means better brain function and better attention.
• More blood flow means better oxygen transfer and more energy.
• More blood flow means better sex. (Nitric Oxide is a key component in erectile function because it stimulates penile blood flow.)

Vitamin C: Ascorbic acid, is Antioxidant Protects against oxidative stress ,Prevents degenerative diseases, Promotes healthy cell development, Promotes calcium absorption, Enables normal tissue growth and repair, Helps prevent blood clotting and bruising Strengthens capillary walls, Promotes Nitric Oxide availability.
As an antioxidant, vitamin C scavenges free radicals in the body and protects tissues from oxidative stress. 1-8 Vitamin C also promotes the absorption of iron, while preventing its oxidation. (9,10);Vitamin C is a vital cofactor to the formation of collagen, the connective tissue that supports arterial walls, skin, bones, and teeth. (5-7) More vitamin C is contained in the adrenal glands than any other organ in the body and is required at higher levels during times of stress. (10-14)

References: 1. Indian J Exp Biol. 1997 Mar;35(3):264-6.2. Am J Clin Nutr. 1996 Jun;63(6):985S-990S;3. FASEB J. 1995 Apr;9(7):526-33. 4. J Am Coll Nutr. 1995 Apr;14(2):124-36. 5. Altern Med Rev. 2003 Nov;8(4):359-77. 6. J Invest Dermatol. 2002 Apr;118(4):565-72. 7. Yale J Biol Med. 1985 Nov-Dec;58(6):553-9. 8. Free Radic Biol Med. 2007 Sep 1;43(5):853-9. 9. Clin Physiol Biochem. 1986;4(1):78-86. 10. Int J Vitam Nutr Res. 1980;50(3):301-8. 11. Res Vet Sci. 1981 Sep;31(2):219-23. 12. In Vivo. 1994 Nov-Dec;8(6):1079-85. 13. Anesteziol Reanimatol. 1990 Sep-Oct;(5):71-4. 14. Psychopharmacology (Berl). 2002 Jan;159(3):319-24

Vitamin D3: Vitamin D3 can be synthesized by humans in the skin upon exposure to ultraviolet-B (UVB) radiation from sunlight. But, due to the winter season, weather conditions, and sun block, the body’s ability to produce optimal vitamin D levels may be inhibited.1 These factors point to the value of taking a daily vitamin D supplement.

Vitamin D has long provided significant support for healthy bone density.2-7 However, scientists have also validated the critical role that vitamin D plays in regulating healthy cell division and differentiation, and its profound effects on human immunity.8-15 These findings link a deficiency of vitamin D to a host of common age-related problems.

1. Photochem Photobiol. 2007 Mar-Apr;83(2):459-63. ;2. Rev Rhum Engl Ed. 1996 Feb;63(2):135-40. 3. Proc Nutr Soc. 2001 May;60(2):283-9 4. J Bone Miner Res. 2003 Jul;18(7):1217-26. ;5. Proc Natl Acad Sci USA. 2002 Oct 15;99(21):13487-91. 6. Steroids. 2001 Mar-May;66(3-5):375-80.;7. Bone. 2006 Oct;39(4):946-53. ;8. Anticancer Res. 2012 Jan;32(1):223-36. 9. Cancer Lett. 2011 Dec 19. [Epub ahead of print] 10. Am J Prev Med. 2011 Jul;41(1):68-74. 11. Clin Rev Allergy Immunol. 2011 Feb 1. [Epub ahead of print] 12. Med Hypotheses. 2011 Dec;77(6):1145-7;13. Dermatoendocrinol. 2011 Jan;3(1):11-7. 14. Mol Cancer. 2011 May 18;10:58. 15. Clin Rev Allergy Immunol. 2011 Feb 1. Vitamin B12: Methylcobalamin Water soluble vitamin, Key role in normal brain and nervous system function, Ensures proper production of key blood cells, Aids in cell function, Supports metabolism of every cell, Enhances Nitric Oxide action.

Methylcobalamin is the form of vitamin B12 that is active in the central nervous system. It is essential for cell growth and replication.1 In some people the liver may not convert cyanocobalamin, the common supplemental form of vitamin B12, into adequate amounts of methylcobalamin needed for proper neuronal functioning.2 Methylcobalamin may exert its neuroprotective effects through enhanced methylation, acceleration of nerve cell growth, or its ability to maintain already healthy homocysteine levels.3,4 For methylcobalamin to be available to the brain, it should be allowed to dissolve in the mouth.

1. Br J Haematol. 2010 Jan;148(2):195-204. 2. Baillieres Clin Haematol. 1995 Sep;8(3):567-601. 3. Pol Merkur Lekarski. 2010 Mar;28(165):236-8. 4. Eur J Clin Nutr. 2010 May;64(5):495-502.

Proprietary Herbal Blend: Including Hawthorn berry extract , Beet Root juice, Celery stalks, and Green tea extract, Nitric Oxide activity Protects against toxins, Increases oxygenation, Increases immune system function, Helps restore vascular function, Enhances exercise performance, Increases integrity of blood vessel walls, Improves coronary blood flow, Enhances oxygen utilization. Hawthorn family have been used in the treatment of cardiovascular diseases.1 Clinical studies have found that standardized extracts of these herbs show promise as supplementary agents for the treatment of left ventricular dysfunction.2-5 Other trials consistently demonstrate hawthorn’s ability to improve exercise tolerance as well as symptoms associated with mild to moderate CHF.6,7 Its effectiveness has been demonstrated repeatedly in double-blind studies.2,4,8 Hawthorn extract shows some beneficial effects in animal and human studies, including enhanced heart pumping efficiency (improved contractility), ACE inhibition, antidysrhythmic effects, and mild reduction in systemic vascular resistance.

1. Fong HH, Bauman JL. Hawthorn. J Cardiovasc Nurs 2002 Jul;16(4):1-8. 2. Schmidt U, et al. Efficacy of the hawthorn (Crataegus) preparation LI 132 in 78 patients with chronic congestive heart failure defined as NYHA functional class II. Phytomedicine 1994 1:17-24. 3. Weikl A, Assmus KD, Neukum-Schmidt A, et al. Crataegus Special Extract WS 1442. Assessment of objective effectiveness in patients with heart failure (NYHA II). Fortschr Med 1996 Aug 30;114(24):291-6. 4. Leuchtgens H. Crataegus Special Extract WS 1442 in NYHA II heart failure. A placebo controlled randomized double-blind study. Fortschr Med 1993 111(20- 21):352-4. 5. Tauchert M, Gildor A, Lipinski J. High- dose Crataegus extract WS 1442 in the treatment of NYHA stage II heart failure. Herz 1999 24(6):465-74. 6. Busse W. Standardized Crataegus extract clinical monograph. Q Rev Nat Med 1996 189-97. 7. Weihmayr T, Ernst E. Therapeutic effectiveness of Crataegus. Fortschr Med 1996 114(1-2):27-9. 8. O’Conolly VM, et al. Treatment of cardiac performance (NYHA stages I to II) in advanced age with standardized cratae gus extract. Fortschr Med 1986 104:805-8.

Green tea has been shown to provide many benefits including:
• Scavenging reactive oxygen species such as superoxide and the hydroxyl and peroxyl radical 1-5
• Fluid-stabilizing properties 6-9
• Possibly promoting weight loss10-15
• Boosting the effectiveness of enzymatic phase II detoxification16-22
• Helping maintain healthy cell proliferation23-37
• Helping maintain healthy blood cholesterol, LDL and triglyceride levels already within normal range38-46
• Enhancing immune function47-63
• Displaying protective effects on brain tissues64-74

1. Chem Res Toxicol. 2003 Sep;16(9):1155-61. 2. Addict Biol. 2002 Jul;7(3):307-14. 3. Arch Biochem Biophys. 1999 Feb 1;362(1):79-86. 4. Phytother Res. 2010 Apr;24(4):503-9. 5. Food Chem Toxicol. 2010 Apr;48(4):1032-9. 6. Free Radic Biol Med. 2003 Mar 15;34(6):648-62. 7. Int J Mol Med. 2005 Oct;16(4):677-81. 8. Biophys J. 2009 Feb;96(3):1026-35. 9. J Physiol Pharmacol. 2008 Dec;59 Suppl 9:217-35. 10. Int J Vitam Nutr Res. 2008 Dec;78(6):275-81. 11. Obesity (Silver Spring). 2007 Jun;15(6):1473-83. 12. In Vivo. 2004 Jan-Feb;18(1):55-62. 13. Br J Nutr. 2005 Sep;94(3):432-6. 14. Obesity (Silver Spring). 2009 Feb;17(2):310-7. 15. J Nutr Biochem. 2011 Jan;22(1):1-7. 16. Carcinogenesis. 2000 Jan;21(1):63-7. 17. Proc Soc Exp Biol Med. 1999 Apr;220(4):239-43. 18. J Nutr. 2008 Aug;138(8):1567S-1571S. 19. Chem Biol Interact. 1995 Dec 22;98(3):283-301. 20. Food Funct. 2011 Feb;2(2):101-10. 21. Curr Drug Metab. 2003 Jun;4(3):241-8. 22. Arch Pharm Res. 2000 Dec; 23(6):605-12. 23. Life Sci. 1998;63(16):1397-403. 24. Invest New Drugs. 2011 Apr;29(2):225-31 25. Expert Rev Anticancer Ther. 2006;6:507–513 26. Front Biosci (Elite Ed). 2009 Jun 1;1:13-25. 27. Cancer Prev Res (Phila Pa). 2009 Jun;2(6):531-7. 28. Nutr Res. 2008 Feb;28(2):92-7. 29. Molecules. 2008 Nov 1;13(11):2704-16. 30. Biomed Res. 2009 Aug;30(4):207-15. 31. Biochem J. 2012 Jan 19. [Epub ahead of print] 32. Hepatol Res. 2012 Jan 3. doi: 10.1111/j.1872-034X.2011.00947.x. [Epub ahead of print] 33. Proteomics. 2011 Dec;11(24):4638-47. 34. Carcinogenesis. 2012 Feb;33(2):377-84. 35. Nutr Cancer. 2012 Jan;64(1):4-22. 36. ISRN Oncol. 2011;2011:403707. Epub 2011 May 16. 37. Anticancer Agents Med Chem. 2011 Oct 25. [Epub ahead of print] 38. Kobe J Med Sci. 2008 May 23;54(1):E62-72. 39. Lipids. 2008 May;43(5):419-29. 40. J Nutr Biochem. 2007 Mar;18(3):179-83. 41. Atherosclerosis. 2007 Jul;193(1):86-93. 42. Arch Intern Med. 2003 Jun 23;163(12):1448-53. 43. Pathophysiology. 2010 Feb;17(1):55-9 44. Cancer Prev Res (Phila). 2012 Feb 1. [Epub ahead of print]45. J Am Diet Assoc. 2011 Nov;111(11):1720-9. 46. Am J Clin Nutr. 2011 Aug;94(2):601-10 47. J Nutr. 2008 Nov;138(11):2111-6. 48. Int J Antimicrob Agents. 2009 May;33(5):473-8. 49. Crit Rev Food Sci Nutr. 2009 May;49(5):463-73. 50. J Agric Food Chem. 2010 Jan 27;58(2):887-94. 51. Free Radic Biol Med. 2009 Sep 1;47(5):636-43. 52. Am J Clin Nutr. 2009 Sep;90(3):672-9. 53. J Gastroenterol. 2000;35 Suppl 12:1-6. 54. Cell Immunol. 2005 Sep;237(1):7-16. 55. Mol Vis. 2011 Feb 18;17:533-42. 56. Cancer Res. 2007 Jan 15;67(2):802-11. 57. J Am Coll Nutr. 2007 Oct;26(5):445-52. 58. Biol Pharm Bull. 2010 Jan;33(1):117-21. 59. PLoS One. 2010 Sep 22;5(9):e12878. 60. Hepatology. 2011 Nov 22. doi: 10.1002/hep.24803. 61. Arch Biochem Biophys. 2010 Sep 1;501(1):65-72. 62. Biochem Pharmacol. 2011 Dec 15;82(12):1807-21. 63. Mol Aspects Med. 2012 Feb;33(1):107-18 64. J Nutr Biochem. 2008 Sep;19(9):619-26. 65. Phytother Res. 2003 Mar;17(3):206-9. 66. CNS Neurosci Ther. 2008 Winter;14(4):352-65. 67. Curr Pharm Des. 2012;18(1):4-14. 68. J Neural Transm. 2012 Jan 4. 69. Front Biosci (Schol Ed). 2012 Jan 1;4:581-98. 70. J Alzheimers Dis. 2011;26(3):507-21. 71. J Alzheimers Dis. 2011;25(2):187-208. 72. J Physiol Biochem. 2010 Jun;66(2):143-51. 73. Brain Res. 2010 Sep 24;1353:28-35. 74. Cent Nerv Syst Agents Med Chem. 2011 Mar 1;11(1):2-7.

L-Citrulline malate: Natural amino acid Naturally creates L-arginine in the urea cycle which then creates Nitric Oxide, Helps in wound healing, Assists immune system.

Acai, and Goji berry juice powders from fruit for naturally sweet flavor.

Additional information

Weight 1.25 lbs
Dimensions 2 x 2 x 4 in


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